Vista Biologicals is capable of providing a host of full-spectrum process development services custom-tailored to the specific needs of the client.

Process Development

Vista Biologicals can assist with the following process development tasks:

Cell Culture

  • Creation of the cell line, either through transformation or transfection with a client-provided vector or by hybridoma fusion
  • Selection of high productivity clones
  • Adaptation to serum-free medium, suspension culture, or both
  • Medium optimization

  • Process design (batch, fed-batch, perfusion)
  • Optimization of fermentation paramteters (feed rate, temperature, pH, DO, etc.)

  • Process design and optimization for yield, purity, endotoxin, viral clearance and cost
  • Assay development